| 1. | Whereas on high level of - 55mv , a continued inward current looked like 相似的慢内向偏转,随之为一缓慢的 |
| 2. | Nacl ( loomm ) in the bath solution inhibited the inward current of wild type and ios5 by 52 . 4 % and 26 . 2 % respectively after 30 minutes treatment 胞外100mmnaci可在处理后30分钟抑制野生型内向k电流的52 4左右, loss的24 |
| 3. | In whole - cell patch clamp recordings , the inward currents were inhibited by 1 mmol / l la3 * , and a23187 which is vector of ca2t increased inward currents 这同样支持了aba诱导保卫细胞产生的h 。 o 。可能是caz “内流的一个上游信号。 |
| 4. | Under the condition of ead generation , the low and high membrane level - 25 and - 55mv of voltage were clamped during the repolarization phase of action potential . on low membrane level of - 25mv , a slow inward current similar to 在低钾灌流并伴有ead的情况下,于动作电位复极相的低及高电位处- 25与- 55mv分别进行电压钳制。 |
| 5. | With holding potential of - - 80mv depolarization beyond - - 30 mv elicited an inward current , peak at + l0 ~ + 20mv and reversed between + 50 mv and + 60mv the peak current was - - 58 . 0i l3 . 4 pa ( n = 7 ) 将细胞膜电位钳制在e0mv阶跃性去极化刺激超过l0mv时引导出内向性钙电流,峰值在去极化刺激至10 20mv时出现,翻转电位在去极化刺激50一、 60mv时出现,峰值平均值为58刀士13 |
| 6. | With holding potential of - - 80 mv depolarization beyond - - 50 mv elicited an inward current , peaked at + l0mv and reversed between + 40 mv and + 60 mv 5 ll m nicardipine , a potent blocker of l - type calcium channel , markedly blocked the " ib 开始出现,峰值在去极化刺激至10 20mv出现,翻转电位为巧0仍0mv 。 l型钙通道特异性阻断剂nicadipine可以明显抑制ib 。 ,并且iv曲线分布在应用nicardipine前后无改受。 |
| 7. | Distinct outward fpsc following the inward fpsc emerged in neurons ^ pll and was abolished by bicuculline ( 50 um ) . bicuculline increased the amplitude and duration of the initial inward fpsc in all age groups and characteristically recruited the polysynaptic second component of fepscs in neurons p11 - p21 . no spontaneous periodic inward current was detected in any age groups after blocking gabaa receptors 在生后11天以上的神经元,内向电流之后出现了明显的外向电流,此外向电流可被gaba受体阻断剂荷包牡丹碱( 50pm )完全阻断,同时iscs的初始内向电流的幅值和时程均明显增加,并且在阻断gaba受体之后,任一年龄组均未观察到自发性周期性的内向电流。 |
| 8. | Similar to hntx - iv , 100 nmol / l hntx - v did n ' t effect the active and inactive kinetics of currents and did n ' t have the effect on the active threshold of sodium channels and the voltage of peak inward currents . however , 100 nmol / l hntx - v caused a 7 . 7 mv hyperpolarizing shift in the voltage midpoint of steady - state sodium channel inactivation 1 / liintx一v也不影响ttx一s钠电流的激活相和失活相,对钠通道的激活闽值和最大激活电压也无明显改变,但能引起钠通道的半稳态失活电压有7 |